The United States, joined by Arab mediators, have sought to conclude an agreement between Israel and Hamas to halt the 14-month-old war in the Gaza Strip where medics say Israeli strikes killed at least 16 Palestinians overnight.
On Tuesday, sources close to the talks in Cairo, said an agreement could be signed in coming days on a ceasefire and release of hostages held in Gaza in return for Palestinian prisoners held by Israel.
Medics said an Israeli air strike killed at least 10 people in a house in the northern town of Beit Lahiya, where army forces have operated since October, while six were killed in separate airstrikes in Gaza City, Nuseirat camp in central areas, and Rafah near the border with Egypt.
There was no immediate comment from the Israeli military spokesman.
CIA Director William Burns was due in Doha on Wednesday for talks. (AP PHOTO)
The US administration, joined by mediators from Egypt and Qatar, has made intensive efforts in recent days to advance the talks before President Joe Biden leaves office next month.
On Wednesday, a Palestinian official close to the negotiations said mediators had narrowed gaps on most of the agreement's clauses but he said Israel had introduced conditions which Hamas rejected. He would not elaborate.
CIA Director William Burns was due in Doha on Wednesday for talks with Qatari Prime Minister Sheikh Mohammed bin Abdulrahman Al Thani on bridging remaining gaps between Israel and Hamas, other knowledgeable sources said. The CIA declined to comment.
Israeli negotiators were in Doha on Monday looking to bridge gaps between Israel and Hamas on a deal Biden outlined in May.
There have been repeated rounds of talks over the past year, all of which have failed, with Israel insisting on retaining a military presence in Gaza and Hamas refusing to release hostages until the troops pulled out.
Qatari Prime Minister Sheikh Mohammed bin Abdulrahman Al Thani is part of the ceasefire talks. (AP PHOTO)
The war in Gaza, triggered by a Hamas-led attack on communities in southern Israel that killed some 1200 people and saw more than 250 abducted as hostages, has sent shockwaves across the Middle East and left Israel isolated internationally.
Israel's campaign has killed more than 45,000 Palestinians, displaced most of the 2.3 million population and reduced much of the coastal enclave to ruins.